| Honorific-Prefix: | The Honourable |
| Clarence Lloyd Gosse | |
| Order: | 25th |
| Office: | Lieutenant Governor of Nova Scotia |
| Predecessor: | Victor de Bedia Oland |
| Successor: | John Elvin Shaffner |
| Term Start: | October 1, 1973 |
| Term End: | December 23, 1978 |
| Governor General: | Roland Michener Jules Léger |
| Premier: | Gerald Regan John Buchanan |
| Birth Name: | Clarence Lloyd Gosse |
| Birth Date: | 20 October 1912 |
| Birth Place: | Spaniard's Bay, Dominion of Newfoundland |
Clarence Lloyd Gosse (October 20, 1912 - December 21, 1996) was a Canadian physician and the 25th Lieutenant Governor of Nova Scotia.
Born in Spaniard's Bay, Newfoundland, he moved to Nova Scotia when he was ten. He graduated from the medical school of Dalhousie University in 1939. During World War II, serving in the Canadian Army Medical Corps, he was a member of one of the first surgical teams in the Battle of Normandy.
After the War, in Halifax, he was a Professor of Urology at Dalhousie University and Chair of the Department of Urology at the Victoria General and Camp Hill hospitals (now the Queen Elizabeth II Health Sciences Centre).
He was Lieutenant Governor of Nova Scotia from 1973 to 1978.
In 1982, he was made an Officer of the Order of Canada.