Big Creek is a stream in Jackson, Cass, Johnson and Henry counties of western Missouri. It is a tributary of the South Grand River.
The stream headwaters are in Jackson County at 38.8819°N -94.3914°W and its confluence with the South Grand River is in Henry County at 38.3889°N -93.8911°W.
Big Creek was named for its large size relative to other nearby creeks.[1]