| Competition: | sanfl |
| Year: | 1959 |
| Teams: | 10 |
| Count: | 20 |
| Mpcount: | 28 |
| Matches: | 76 |
| Attendance: | 863466 |
| Highattend: | 48,884 (Grand Final, vs.) |
| Top Goal Scorer: | Wally Dittmar (74 goals) |
| Magarey Medal: | Len Fitzgerald |
| Prevseason: | 1958 |
| Nextseason: | 1960 |
The 1959 South Australian National Football League season was the 80th season of the top-level Australian rules football competition in South Australia.
By winning the 1959 SANFL Grand Final, Port Adelaide set the Australian record of six consecutive Grand Final victories in a top level state competition when it defeated West Adelaide by 10 points.
See main article: 1959 SANFL Grand Final.